TY - GEN
T1 - Variable interaction networks in medical data
AU - Winkler, Stephan
AU - Affenzeller, Michael
AU - Kronberger, Gabriel
AU - Kommenda, Michael
AU - Wagner, Stefan
AU - Jacak, Witold
AU - Stekel, Herbert
PY - 2012
Y1 - 2012
N2 - In this paper we describe the identification of variable interaction networks in a medical data set. The main goal is to generate mathematical models for standard blood parameters as well as tumor markers using other available parameters in this data set. For each variable we identify those variables that are most relevant for modeling it; relevance of a variable can in this context be defined via the frequency of its occurrence in models identified by evolutionary machine learning methods or via the decrease in modeling quality after removing it from the data set. Several data based modeling approaches implemented in HeuristicLab have been applied for identifying estimators for selected tumor markers and cancer diagnoses: Linear regression and support vector machines (optimized using evolutionary algorithms) as well as genetic programming.
AB - In this paper we describe the identification of variable interaction networks in a medical data set. The main goal is to generate mathematical models for standard blood parameters as well as tumor markers using other available parameters in this data set. For each variable we identify those variables that are most relevant for modeling it; relevance of a variable can in this context be defined via the frequency of its occurrence in models identified by evolutionary machine learning methods or via the decrease in modeling quality after removing it from the data set. Several data based modeling approaches implemented in HeuristicLab have been applied for identifying estimators for selected tumor markers and cancer diagnoses: Linear regression and support vector machines (optimized using evolutionary algorithms) as well as genetic programming.
KW - Data mining
KW - Evolutionary algorithms
KW - Medical data analysis
KW - Variable interaction networks
UR - http://www.scopus.com/inward/record.url?scp=84871516294&partnerID=8YFLogxK
M3 - Conference contribution
SN - 9788897999096
T3 - 24th European Modeling and Simulation Symposium, EMSS 2012
SP - 265
EP - 270
BT - 24th European Modeling and Simulation Symposium, EMSS 2012
T2 - 24th European Modeling and Simulation Symposium, EMSS 2012
Y2 - 19 September 2012 through 21 September 2012
ER -