Robust tube-based predictive control of blood glucose concentration in type 1 diabetes

Harald Kirchsteiger; Luigi Del Re

doi:10.1109/CDC.2013.6760189

Robust tube-based predictive control of blood glucose concentration in type 1 diabetes

Harald Kirchsteiger
, Luigi Del Re

Research output: Chapter in Book/Report/Conference proceedings › Conference contribution › peer-review

8 Citations (Scopus)

Abstract

This paper investigates the applicability of tube-based robust MPC to control the blood glucose concentration in type 1 diabetic subjects through simulation studies. An existing, widely used nonlinear time-invariant metabolic simulation model is adopted and extended with several physiologically motivated uncertainties to account for the underlying intra-patient variability observed in real patients. Results on a virtual subject show that robustness to uncertainties can be improved and the risk of hypoglycemia reduced, without increasing the online computational demands compared to the conventional model predictive control approach.

Original language	English
Title of host publication	2013 IEEE 52nd Annual Conference on Decision and Control, CDC 2013
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	2084-2089
Number of pages	6
ISBN (Print)	9781467357173
DOIs	https://doi.org/10.1109/CDC.2013.6760189
Publication status	Published - 2013
Externally published	Yes
Event	52nd IEEE Conference on Decision and Control, CDC 2013 - Florence, Italy Duration: 10 Dec 2013 → 13 Dec 2013

Publication series

Name	Proceedings of the IEEE Conference on Decision and Control
ISSN (Print)	0743-1546
ISSN (Electronic)	2576-2370

Conference

Conference	52nd IEEE Conference on Decision and Control, CDC 2013
Country/Territory	Italy
City	Florence
Period	10.12.2013 → 13.12.2013

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Access to Document

10.1109/CDC.2013.6760189

Cite this

Kirchsteiger, H., & Del Re, L. (2013). Robust tube-based predictive control of blood glucose concentration in type 1 diabetes. In 2013 IEEE 52nd Annual Conference on Decision and Control, CDC 2013 (pp. 2084-2089). Article 6760189 (Proceedings of the IEEE Conference on Decision and Control). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/CDC.2013.6760189

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title = "Robust tube-based predictive control of blood glucose concentration in type 1 diabetes",

abstract = "This paper investigates the applicability of tube-based robust MPC to control the blood glucose concentration in type 1 diabetic subjects through simulation studies. An existing, widely used nonlinear time-invariant metabolic simulation model is adopted and extended with several physiologically motivated uncertainties to account for the underlying intra-patient variability observed in real patients. Results on a virtual subject show that robustness to uncertainties can be improved and the risk of hypoglycemia reduced, without increasing the online computational demands compared to the conventional model predictive control approach.",

author = "Harald Kirchsteiger and \{Del Re\}, Luigi",

year = "2013",

doi = "10.1109/CDC.2013.6760189",

language = "English",

isbn = "9781467357173",

series = "Proceedings of the IEEE Conference on Decision and Control",

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pages = "2084--2089",

booktitle = "2013 IEEE 52nd Annual Conference on Decision and Control, CDC 2013",

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note = "52nd IEEE Conference on Decision and Control, CDC 2013 ; Conference date: 10-12-2013 Through 13-12-2013",

}

Kirchsteiger, H & Del Re, L 2013, Robust tube-based predictive control of blood glucose concentration in type 1 diabetes. in 2013 IEEE 52nd Annual Conference on Decision and Control, CDC 2013., 6760189, Proceedings of the IEEE Conference on Decision and Control, Institute of Electrical and Electronics Engineers Inc., pp. 2084-2089, 52nd IEEE Conference on Decision and Control, CDC 2013, Florence, Italy, 10.12.2013. https://doi.org/10.1109/CDC.2013.6760189

Robust tube-based predictive control of blood glucose concentration in type 1 diabetes. / Kirchsteiger, Harald; Del Re, Luigi.
2013 IEEE 52nd Annual Conference on Decision and Control, CDC 2013. Institute of Electrical and Electronics Engineers Inc., 2013. p. 2084-2089 6760189 (Proceedings of the IEEE Conference on Decision and Control).

Research output: Chapter in Book/Report/Conference proceedings › Conference contribution › peer-review

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T1 - Robust tube-based predictive control of blood glucose concentration in type 1 diabetes

AU - Kirchsteiger, Harald

AU - Del Re, Luigi

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N2 - This paper investigates the applicability of tube-based robust MPC to control the blood glucose concentration in type 1 diabetic subjects through simulation studies. An existing, widely used nonlinear time-invariant metabolic simulation model is adopted and extended with several physiologically motivated uncertainties to account for the underlying intra-patient variability observed in real patients. Results on a virtual subject show that robustness to uncertainties can be improved and the risk of hypoglycemia reduced, without increasing the online computational demands compared to the conventional model predictive control approach.

AB - This paper investigates the applicability of tube-based robust MPC to control the blood glucose concentration in type 1 diabetic subjects through simulation studies. An existing, widely used nonlinear time-invariant metabolic simulation model is adopted and extended with several physiologically motivated uncertainties to account for the underlying intra-patient variability observed in real patients. Results on a virtual subject show that robustness to uncertainties can be improved and the risk of hypoglycemia reduced, without increasing the online computational demands compared to the conventional model predictive control approach.

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SN - 9781467357173

T3 - Proceedings of the IEEE Conference on Decision and Control

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BT - 2013 IEEE 52nd Annual Conference on Decision and Control, CDC 2013

PB - Institute of Electrical and Electronics Engineers Inc.

T2 - 52nd IEEE Conference on Decision and Control, CDC 2013

Y2 - 10 December 2013 through 13 December 2013

ER -

Robust tube-based predictive control of blood glucose concentration in type 1 diabetes

Abstract

Publication series

Conference

UN SDGs

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