TY - JOUR
T1 - Multimodal noncontact photoacoustic and optical coherence tomography imaging using wavelength-division multiplexing
AU - Berer, Thomas
AU - Leiss-Holzinger, Elisabeth
AU - Hochreiner, Armin
AU - Bauer-Marschallinger, Johannes
AU - Buchsbaum, Andreas
PY - 2015/4/1
Y1 - 2015/4/1
N2 - We present multimodal noncontact photoacoustic (PA) and optical coherence tomography (OCT) imaging. PA signals are acquired remotely on the surface of a specimen with a Mach-Zehnder interferometer. The interferometer is realized in a fiber-optic network using a fiber laser at 1550 nm as the source. In the same fiber-optic network, a spectral-domain OCT system is implemented. The OCT system utilizes a supercontinuum light source at 1310 nm and a spectrometer with an InGaAs line array detector. Light from the fiber laser and the OCT source is multiplexed into one fiber using a wavelength-division multiplexer; the same objective is used for both imaging modalities. Reflected light is spectrally demultiplexed and guided to the respective imaging systems. We demonstrate two-dimensional and three-dimensional imaging on a tissue-mimicking sample and a chicken skin phantom. The same fiber network and same optical components are used for PA and OCT imaging, and the obtained images are intrinsically coregistered.
AB - We present multimodal noncontact photoacoustic (PA) and optical coherence tomography (OCT) imaging. PA signals are acquired remotely on the surface of a specimen with a Mach-Zehnder interferometer. The interferometer is realized in a fiber-optic network using a fiber laser at 1550 nm as the source. In the same fiber-optic network, a spectral-domain OCT system is implemented. The OCT system utilizes a supercontinuum light source at 1310 nm and a spectrometer with an InGaAs line array detector. Light from the fiber laser and the OCT source is multiplexed into one fiber using a wavelength-division multiplexer; the same objective is used for both imaging modalities. Reflected light is spectrally demultiplexed and guided to the respective imaging systems. We demonstrate two-dimensional and three-dimensional imaging on a tissue-mimicking sample and a chicken skin phantom. The same fiber network and same optical components are used for PA and OCT imaging, and the obtained images are intrinsically coregistered.
KW - Imaging
KW - fiber-optics imaging.
KW - interferometry
KW - multimodal imaging
KW - optical coherence tomography
KW - remote sensing
UR - http://www.scopus.com/inward/record.url?scp=84929493092&partnerID=8YFLogxK
U2 - 10.1117/1.JBO.20.4.046013
DO - 10.1117/1.JBO.20.4.046013
M3 - Article
SN - 1560-2281
VL - 20
JO - Journal of Biomedical Optics
JF - Journal of Biomedical Optics
IS - 4
M1 - 046013
ER -