MS Annika 2.0 Identifies Cross-Linked Peptides in MS2–MS3-Based Workflows at High Sensitivity and Specificity

Keyphrases

• Search Engine 100%
• High Specificity 100%
• High Sensitivity 100%
• Cross-linked Peptides 100%
• False Discovery Rate 66%
• Protein-protein Interaction 33%
• Proteomics Data 33%
• Cross-linker 33%
• Cross-linking Mass Spectrometry 33%
• Protein Structure 33%
• Mass Spectrometry Analysis 33%
• Scoring Function 33%
• Search Ability 33%
• Search Algorithm 33%
• Target-decoy Approach 33%
• XlinkX 33%
• ProteomeXchange 33%
• False Positive Hits 33%
• Different Datasets 33%

Biochemistry, Genetics and Molecular Biology

• Cross-Link 100%
• Search Engine 60%
• Mass Spectrometry 40%
• Proteomics 20%

Immunology and Microbiology

• Cross Linking 100%
• Search Engine 60%