TY - GEN
T1 - Knowledge-based systems for biomedical laboratory applications
AU - Kern, Thomas
AU - Breuer, Karin
AU - Siegl, Doris
AU - Straßer, Wolfgang
N1 - Copyright:
Copyright 2011 Elsevier B.V., All rights reserved.
PY - 2004
Y1 - 2004
N2 - The research project BIO MIS focuses on three different biomedical problem domains, each dealing with huge amounts of data. In order to validate new input data and create a proposal system this data is used to build up an adaptive knowledge-base. The knowledge is structured by creating clusters of similar items and searching relationships among them. In the classification process system input is compared to the generated cluster profiles. If it affirms similarity it is assigned to the according cluster and, in that way, adapts the knowledge-base to recent circumstances. The clustering process is non-trivial since we mainly have to deal with non-metric laboratory data and cannot use standard clustering algorithms. Our new clustering approach is exemplified on the "LabExpert" package; a system part of one subproject implementing a validation system for large-scale laboratory data.
AB - The research project BIO MIS focuses on three different biomedical problem domains, each dealing with huge amounts of data. In order to validate new input data and create a proposal system this data is used to build up an adaptive knowledge-base. The knowledge is structured by creating clusters of similar items and searching relationships among them. In the classification process system input is compared to the generated cluster profiles. If it affirms similarity it is assigned to the according cluster and, in that way, adapts the knowledge-base to recent circumstances. The clustering process is non-trivial since we mainly have to deal with non-metric laboratory data and cannot use standard clustering algorithms. Our new clustering approach is exemplified on the "LabExpert" package; a system part of one subproject implementing a validation system for large-scale laboratory data.
UR - http://www.scopus.com/inward/record.url?scp=16244395512&partnerID=8YFLogxK
U2 - 10.1109/IRI.2004.1431480
DO - 10.1109/IRI.2004.1431480
M3 - Conference contribution
SN - 0780388194
SN - 9780780388192
T3 - Proceedings of the 2004 IEEE International Conference on Information Reuse and Integration, IRI-2004
SP - 314
EP - 319
BT - Proceedings of the 2004 IEEE International Conference on Information Reuse and Integration, IRI-2004
A2 - Memon, A.M.
A2 - Zhao, N.
PB - IEEE Systems, Man, and Cybernetics Society (SMC)
T2 - Proceedings of the 2004 IEEE International Conference on Information Reuse and Integration, IRI-2004
Y2 - 8 November 2004 through 10 November 2004
ER -