In-Vitro and In-Vivo Measurement of Iron Concentration in Human Hepatic Tissue by Magnetic Induction Methods

Roberto Casanas, Hermann Scharfetter, A Altes, A Remacha, P Sarda, J Sierra, Robert Merwa, Karl Hollaus, Javier Rosell

Research output: Contribution to conferenceAbstractpeer-review

Abstract

We study the feasibility of a new non-invasive method to measure hepatic iron overload using a magnetic induction (MI) based system. Experimental data (in vitro and in-vivo) were acquired with a custom measurement system using an excitation coil and a planar gradiometer as receiver. We estimate the response of the system using analytical expressions for the in-vitro study and the finite element method (FEM) for the in-vivo study. Seventeen in-vitro liver samples have been measured. Measurements were compared with a biochemical iron estimation procedure. A significant agreement is observed (R=0.94, P<0.001) between biochemical and MI results. The systems and procedures were adapted for in-vivo measurements. Ten patients and 8 volunteers were measured. We show the results for these two groups and two different estimators.

Original languageEnglish
Pages3064-3067
Number of pages4
DOIs
Publication statusPublished - 2003
EventXXV Annual International Conference of the IEEE Engineering in Medicine and Biology - Cancun, Mexico
Duration: 17 Sep 200321 Sep 2003

Conference

ConferenceXXV Annual International Conference of the IEEE Engineering in Medicine and Biology
CountryMexico
CityCancun
Period17.09.200321.09.2003

Keywords

  • Heinodiroinatosis
  • Hepatic iron
  • Magnetic induction

Fingerprint Dive into the research topics of 'In-Vitro and In-Vivo Measurement of Iron Concentration in Human Hepatic Tissue by Magnetic Induction Methods'. Together they form a unique fingerprint.

Cite this