Exploring the NeuroIS Potential for Generative Artificial Intelligence: Findings from a Literature Review

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Abstract

Generative Artificial Intelligence (GenAI) is transforming human–computer interaction, shaping behavior as well as cognitive and emotional processes. This paper explores how Neuro-Information Systems (NeuroIS) measurements can be applied to the study of GenAI, addressing their role in human-AI interaction. Through a literature review, we identify 21 papers using neurophysiological measurements, including autonomic nervous system (ANS) markers (e.g., eye-tracking), brain imaging (e.g., EEG), and multimodal approaches such as combining eye tracking and EEG. Our findings highlight main research themes, including cognitive offloading, trust, and decision-making biases in human interaction with GenAI. While research on this topic is becoming more prominent, neurophysiological investigations remain limited. We anticipate that measures of brain and ANS system activity, as well as hormone measures, will play an increasing role in future empirical research on GenAI. This study contributes to the advancement of NeuroIS by providing a structured foundation for better understanding the role of GenAI in this research field.
Original languageEnglish
Title of host publicationInformation Systems and Neuroscience: NeuroIS Retreat 2025, Vienna, Austria
EditorsFred D. Davis, René Riedl, Jan vom Brocke, Pierre-Majorique Léger, Adriane B. Randolph, Gernot R. Müller-Putz
Place of PublicationCham
PublisherSpringer
Pages11-25
DOIs
Publication statusPublished - 2 Jan 2026
EventNeuroIS Retreat 2025 - Austria Trend Hotel Schloss Wilhelminenberg, Vienna, Austria
Duration: 26 May 202528 May 2025
https://www.neurois.org/neurois-retreat-2025

Publication series

NameLecture Notes in Information Systems and Organisation
PublisherSpringer
Volume9
ISSN (Print)2195-4968
ISSN (Electronic)2195-4976

Conference

ConferenceNeuroIS Retreat 2025
Country/TerritoryAustria
CityVienna
Period26.05.202528.05.2025
Internet address

Keywords

  • Generative AI (GenAI)
  • Human-AI Interaction
  • Literature Review
  • Neuro-Information Systems (NeuroIS)
  • Neurophysiological Measurements

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