Contactless photoacoustic imaging of biological samples

Thomas Berer, Armin Hochreiner, Hubert Grün, Peter Burgholzer

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


In this paper we report on remote photoacoustic imaging using an interferometric technique. By utilizing a twowave mixing interferometer ultrasonic displacements are measured without any physical contact to the sample. This technique allows measurement of the displacements also on rough surfaces. Mixing a plane reference beam with the speckled beam originating from the sample surface is done in a Bi 12SiO 20 photorefractive crystal. After data acquisition the structure of the specimen is reconstructed using a Fourier-domain synthetic focusing aperture technique. We show three-dimensional imaging on tissue-mimicking phantoms and biological samples. Furthermore, we show remote photoacoustic measurements on a human forearm in-vivo.

Original languageEnglish
JournalProceedings of SPIE
Publication statusPublished - Feb 2012
EventSPIE BIOS 2012 - San Francisco, United States
Duration: 21 Jan 201226 Jan 2012


  • Photoacoustic imaging
  • Photorefractive crystal
  • Remote imaging
  • Remote ultrasound detection
  • Twowave mixing


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