Applied data mining: From biomarker discovery to decision support systems

Melanie Osl, Michael Netzer, Stephan Dreiseitl, C. Baumgartner

Research output: Chapter in Book/Report/Conference proceedingsChapterpeer-review

4 Citations (Scopus)

Abstract

This chapter provides an overview of emerging bioinformatics methods for the biomarker discovery process and medical decision support. It introduces study design consideration and bioanalytic concepts for generating biomedical data, followed by various data mining and information retrieval procedures such as feature selection, classification as well as statistical and clinical validation. The reviewed methods are illustrated by real examples from preclinical and clinical studies, and the application in medical decision making is discussed. This chapter is anticipated to address to those with a bioinformatics background as well as biomedical researchers who are interested in the application of computational methods in biomarker discovery and medical decision making.

Original languageEnglish
Title of host publicationComputational Medicine
Subtitle of host publicationTools and Challenges
PublisherSpringer
Pages173-184
Number of pages12
Volume9783709109472
ISBN (Electronic)9783709109472
ISBN (Print)3709109469, 9783709109465
DOIs
Publication statusPublished - 1 Mar 2012

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