SHP-1 associates with both platelet-derived growth factor receptor and the p85 subunit of phosphatidylinositol 3-kinase

Keyphrases

• Phosphoinositide 3-kinase (PI3K) 100%
• Platelet-derived Growth Factor Receptor (PDGFR) 100%
• SHP-1 100%
• Non-hematopoietic Cells 27%
• MCF-7 18%
• Negatively Regulate 18%
• Platelet-derived Growth factor-BB (PDGF-BB) 18%
• Promoter Activation 18%
• C-Fos 18%
• Hematopoietic Cells 18%
• Overexpression 9%
• Receptor-mediated 9%
• Tyrosine 9%
• Cytokine Receptor 9%
• Peptide Competition 9%
• Protein Tyrosine Phosphatase 1B (PTP1B) 9%
• Epithelial Cell Line 9%
• Co-immunoprecipitation (co-IP) 9%
• Malignant Epithelial Cells 9%
• Src Homology 2 9%
• Src Homology 2 Domain 9%
• Multiple Cytokines 9%

Immunology and Microbiology

• Platelet Derived Growth Factor 100%
• Kinase 100%
• Phosphotransferase 100%
• Hematopoietic Cell 55%
• Promoter Region 22%
• Oncogene C Fos 22%
• Tyrosine 22%
• Amino Terminal Sequence 11%
• Immunoprecipitation 11%
• Epithelial Cell Line 11%
• Cytokine Receptor 11%
• Peptides 11%
• Phosphatase 11%

Biochemistry, Genetics and Molecular Biology

• Platelet-Derived Growth Factor Receptor 100%
• Phosphoinositide 3-Kinase 100%
• Hematopoietic Cell 71%
• Promoter Region 28%
• C-Fos 28%
• Platelet-Derived Growth Factor 28%
• N-Terminus 14%
• Immunoprecipitation 14%
• Tyrosine 14%
• Cytokine Receptor 14%
• Protein Tyrosine Phosphatase 14%
• Peptide 14%