Robust tube-based predictive control of blood glucose concentration in type 1 diabetes

Harald Kirchsteiger; Luigi Del Re

doi:10.1109/CDC.2013.6760189

Robust tube-based predictive control of blood glucose concentration in type 1 diabetes

Harald Kirchsteiger
, Luigi Del Re

Publikation: Beitrag in Buch/Bericht/Tagungsband › Konferenzbeitrag › Begutachtung

8 Zitate (Scopus)

Abstract

This paper investigates the applicability of tube-based robust MPC to control the blood glucose concentration in type 1 diabetic subjects through simulation studies. An existing, widely used nonlinear time-invariant metabolic simulation model is adopted and extended with several physiologically motivated uncertainties to account for the underlying intra-patient variability observed in real patients. Results on a virtual subject show that robustness to uncertainties can be improved and the risk of hypoglycemia reduced, without increasing the online computational demands compared to the conventional model predictive control approach.

Originalsprache	Englisch
Titel	2013 IEEE 52nd Annual Conference on Decision and Control, CDC 2013
Herausgeber (Verlag)	Institute of Electrical and Electronics Engineers Inc.
Seiten	2084-2089
Seitenumfang	6
ISBN (Print)	9781467357173
DOIs	https://doi.org/10.1109/CDC.2013.6760189
Publikationsstatus	Veröffentlicht - 2013
Extern publiziert	Ja
Veranstaltung	52nd IEEE Conference on Decision and Control, CDC 2013 - Florence, Italien Dauer: 10 Dez. 2013 → 13 Dez. 2013

Publikationsreihe

Name	Proceedings of the IEEE Conference on Decision and Control
ISSN (Print)	0743-1546
ISSN (elektronisch)	2576-2370

Konferenz

Konferenz	52nd IEEE Conference on Decision and Control, CDC 2013
Land/Gebiet	Italien
Ort	Florence
Zeitraum	10.12.2013 → 13.12.2013

UN SDGs

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SDG 3 – Gute Gesundheit und Wohlergehen

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10.1109/CDC.2013.6760189

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Kirchsteiger, H., & Del Re, L. (2013). Robust tube-based predictive control of blood glucose concentration in type 1 diabetes. in 2013 IEEE 52nd Annual Conference on Decision and Control, CDC 2013 (S. 2084-2089). Artikel 6760189 (Proceedings of the IEEE Conference on Decision and Control). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/CDC.2013.6760189

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title = "Robust tube-based predictive control of blood glucose concentration in type 1 diabetes",

abstract = "This paper investigates the applicability of tube-based robust MPC to control the blood glucose concentration in type 1 diabetic subjects through simulation studies. An existing, widely used nonlinear time-invariant metabolic simulation model is adopted and extended with several physiologically motivated uncertainties to account for the underlying intra-patient variability observed in real patients. Results on a virtual subject show that robustness to uncertainties can be improved and the risk of hypoglycemia reduced, without increasing the online computational demands compared to the conventional model predictive control approach.",

author = "Harald Kirchsteiger and \{Del Re\}, Luigi",

year = "2013",

doi = "10.1109/CDC.2013.6760189",

language = "English",

isbn = "9781467357173",

series = "Proceedings of the IEEE Conference on Decision and Control",

publisher = "Institute of Electrical and Electronics Engineers Inc.",

pages = "2084--2089",

booktitle = "2013 IEEE 52nd Annual Conference on Decision and Control, CDC 2013",

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note = "52nd IEEE Conference on Decision and Control, CDC 2013 ; Conference date: 10-12-2013 Through 13-12-2013",

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Kirchsteiger, H & Del Re, L 2013, Robust tube-based predictive control of blood glucose concentration in type 1 diabetes. in 2013 IEEE 52nd Annual Conference on Decision and Control, CDC 2013., 6760189, Proceedings of the IEEE Conference on Decision and Control, Institute of Electrical and Electronics Engineers Inc., S. 2084-2089, 52nd IEEE Conference on Decision and Control, CDC 2013, Florence, Italien, 10.12.2013. https://doi.org/10.1109/CDC.2013.6760189

Robust tube-based predictive control of blood glucose concentration in type 1 diabetes. / Kirchsteiger, Harald; Del Re, Luigi.
2013 IEEE 52nd Annual Conference on Decision and Control, CDC 2013. Institute of Electrical and Electronics Engineers Inc., 2013. S. 2084-2089 6760189 (Proceedings of the IEEE Conference on Decision and Control).

Publikation: Beitrag in Buch/Bericht/Tagungsband › Konferenzbeitrag › Begutachtung

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AB - This paper investigates the applicability of tube-based robust MPC to control the blood glucose concentration in type 1 diabetic subjects through simulation studies. An existing, widely used nonlinear time-invariant metabolic simulation model is adopted and extended with several physiologically motivated uncertainties to account for the underlying intra-patient variability observed in real patients. Results on a virtual subject show that robustness to uncertainties can be improved and the risk of hypoglycemia reduced, without increasing the online computational demands compared to the conventional model predictive control approach.

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Robust tube-based predictive control of blood glucose concentration in type 1 diabetes

Abstract

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