Increasing the sensitivity of cancer predictors using confidence based ensemble modeling

Michael Affenzeller, Karin Zölzer, Stephan M. Winkler, Erwin Hopf, Herbert Stekel, Rupert Frechinger, Stefan Wagner

Publikation: Beitrag in Buch/Bericht/TagungsbandKonferenzbeitragBegutachtung

1 Zitat (Scopus)

Abstract

This paper discusses the use of symbolic regression based ensemble modeling for obtaining more sensitive cancer predictors. The ensemble models are generated on the basis of blood parameters acting as model inputs which have been coupled with diagnosis data in order to predict breast cancer. In addition to previous works this contribution focuses on the use of ensemble predictors in order to achieve more sensitive models. For achieving this goal the best models in terms of accuracy, sensitivity and in terms of a combined measure are selected based on training data in order to analyze to which extent the more sensitive model behavior is also reflected on test data. In addition to the a-posteriori selection of ensemble models with certain properties first results are shown that have been achieved with a new evaluation function which favors more sensitive predictors and guides the search towards more sensitive models already in the model generation phase.

OriginalspracheEnglisch
TitelComputer Aided Systems Theory – EUROCAST 2015 - 15th International Conference, Revised Selected Papers
Redakteure/-innenFranz Pichler, Roberto Moreno-Díaz, Alexis Quesada-Arencibia
Herausgeber (Verlag)Springer
Seiten350-358
Seitenumfang9
ISBN (Print)9783319273396
DOIs
PublikationsstatusVeröffentlicht - 2015
Veranstaltung15th International Conference on Computer Aided Systems Theory, Eurocast 2015 - Las Palmas, Gran Canaria, Spanien
Dauer: 8 Feb. 201513 Feb. 2015
http://eurocast2015.fulp.ulpgc.es/

Publikationsreihe

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Band9520
ISSN (Print)0302-9743
ISSN (elektronisch)1611-3349

Konferenz

Konferenz15th International Conference on Computer Aided Systems Theory, Eurocast 2015
Land/GebietSpanien
OrtLas Palmas, Gran Canaria
Zeitraum08.02.201513.02.2015
Internetadresse

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