In-Vitro and In-Vivo Measurement of Iron Concentration in Human Hepatic Tissue by Magnetic Induction Methods

Roberto Casanas, Hermann Scharfetter, A Altes, A Remacha, P Sarda, J Sierra, Robert Merwa, Karl Hollaus, Javier Rosell

Publikation: KonferenzbeitragAbstractBegutachtung

Abstract

We study the feasibility of a new non-invasive method to measure hepatic iron overload using a magnetic induction (MI) based system. Experimental data (in vitro and in-vivo) were acquired with a custom measurement system using an excitation coil and a planar gradiometer as receiver. We estimate the response of the system using analytical expressions for the in-vitro study and the finite element method (FEM) for the in-vivo study. Seventeen in-vitro liver samples have been measured. Measurements were compared with a biochemical iron estimation procedure. A significant agreement is observed (R=0.94, P<0.001) between biochemical and MI results. The systems and procedures were adapted for in-vivo measurements. Ten patients and 8 volunteers were measured. We show the results for these two groups and two different estimators.

OriginalspracheEnglisch
Seiten3064-3067
Seitenumfang4
DOIs
PublikationsstatusVeröffentlicht - 2003
VeranstaltungXXV Annual International Conference of the IEEE Engineering in Medicine and Biology - Cancun, Mexiko
Dauer: 17 Sep. 200321 Sep. 2003

Konferenz

KonferenzXXV Annual International Conference of the IEEE Engineering in Medicine and Biology
Land/GebietMexiko
OrtCancun
Zeitraum17.09.200321.09.2003

Fingerprint

Untersuchen Sie die Forschungsthemen von „In-Vitro and In-Vivo Measurement of Iron Concentration in Human Hepatic Tissue by Magnetic Induction Methods“. Zusammen bilden sie einen einzigartigen Fingerprint.

Zitieren