Engineered hyperphosphorylation of the β2-adrenoceptor prolongs arrestin-3 binding and induces arrestin internalization

Keyphrases

• Adrenoceptors 100%
• Hyperphosphorylation 100%
• Arrestin 100%
• Arrestin-3 100%
• Phosphorylation Sites 22%
• Receptor Phosphorylation 22%
• Fluorescence Recovery 11%
• Plasma Membrane 11%
• Phosphorylation 11%
• Single-molecule Fluorescence Resonance Energy Transfer (smFRET) 11%
• G Protein-coupled Receptor 11%
• Colocalization 11%
• Endosome 11%
• Receptor Complex 11%
• 4-fold 11%
• Receptor Desensitization 11%
• Vasopressin V2 Receptor 11%
• Phosphorylation Pattern 11%
• C-terminal Tail 11%
• Isoprenaline 11%
• Carboxyl Terminal 11%
• Receptor Modification 11%

Neuroscience

• Internalization 100%
• Retina S Antigen 100%
• Hyperphosphorylation 100%
• Adrenergic Receptor 100%
• Receptor 56%
• phosphorylation 18%
• Receptor Phosphorylation 12%
• C-Terminus 12%
• Energy Transfer 6%
• G Protein Coupled Receptor 6%
• Cell Membrane 6%
• Receptor down Regulation 6%
• Fluorescence Recovery after Photobleaching 6%
• Isoprenaline 6%
• Vasopressin 6%

Biochemistry, Genetics and Molecular Biology

• Internalization 100%
• Arrestin 100%
• Hyperphosphorylation 100%
• Adrenergic Receptor 100%
• phosphorylation 31%
• C-Terminus 12%
• Wild Type 12%
• Cell Membrane 6%
• Fluorescence Recovery after Photobleaching 6%
• Fluorescence Resonance Energy Transfer 6%
• G Protein Coupled Receptor 6%
• Receptor down Regulation 6%
• Vasopressin 6%
• Isoprenaline 6%
• Colocalization 6%